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Description Mirapex (generic name: Pramipexole; brand mames include: Mirapexin / Sifrol) belongs to a class of drugs known as dopamine agonists. Mirapex is indicated for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS). Mirapex has been shown to relieve the frequency and severity of the symptoms of primary RLS, including the urge to move one's legs. It provides effective long-term relief. In clinical trials patients taking Mirapex for RLS have shown a significant improvement in the frequency and severity of many RLS symptoms. In a clinical trial, 72% of patients on Mirapex experienced significant symptom improvements. Mirapex is also approved by the FDA for treating the signs and symptoms of Parkinson's disease. In a clinical study, patients recently diagnosed with Parkinson's disease had improvement in their activities of daily living. Mirapex can be used alone, or in combination with other therapies, and is effective in treating both early and advanced stages of the disease. Recommendations Follow the directions for using this medicine provided by your doctor. Take Mirapex exactly as directed. Parkinson's disease: Mirapex is taken 3 times a day. Dosages should be increased gradually from a starting dose of 0.375 mg/day given in three divided doses and should not be increased more frequently than every 5 to 7 days. Restless Legs Syndrome: The recommended starting dose of Mirapex tablets is 0.125 mg taken once daily 2-3 hours before bedtime. For patients requiring additional symptomatic relief, the dose may be increased every 4-7 days. Precautions Tell your doctor before taking Mirapex, if: you are allergic to any medicines; you have any serious medical conditions including kidney problems; you are pregnant or breast-feeding. Ingredients Active ingredient: pramipexole dihydrochloride.
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